| Characteristic | Details |
|---|---|
| Active Ingredient | Sildenafil Citrate |
| Available Dosages | 25 mg, 50 mg, 100 mg |
| Usage | Treats erectile dysfunction (ED) |
| Administration | Oral |
| More Information on Silagra | |
Chemical Structure
The active ingredient in Silagra is Sildenafil Citrate, a compound classified as a PDE5 inhibitor. Its molecular structure features a pyrazolo-pyrimidinone core. Sildenafil shares structural similarities with the nucleoside guanosine, binding selectively to phosphodiesterase-5 (PDE5) enzymes. This selective inhibition increases cyclic guanosine monophosphate (cGMP) levels, enhancing nitric oxide effects. These effects facilitate smooth muscle relaxation in the corpus cavernosum and promote blood flow, crucial for achieving and maintaining an erection.
Correct Use
Silagra 100 mg, when taken appropriately, can significantly alleviate erectile dysfunction symptoms. Patients should administer it orally, approximately one hour prior to anticipated sexual activity. The drug exhibits a 4-5 hour window of efficacy. This timing optimizes its effect while minimizing the risk of adverse events. A glass of water ensures rapid absorption.
Silagra should not be ingested more than once within a 24-hour period. Initiating treatment at a lower dose such as Silagra 50 mg can help gauge individual tolerance. Adjustments can follow based on therapeutic response and side effect profile.
Warnings & Precautions
Patients must adhere to safety guidelines. Those with cardiovascular conditions, especially those taking nitrates, should exercise caution. Combining Silagra with nitrate-based medications may provoke significant hypotension. Individuals with renal or hepatic impairment also require dose adjustments.
Assessing potential contraindications such as severe cardiovascular conditions, recent stroke, or unstable angina is vital. Regular follow-up with healthcare professionals ensures safe and effective usage of Silagra.
Silagra Interactions
Interaction with other drugs can alter Silagra’s effectiveness. Patients should disclose all medications they are currently taking. The concurrent use of other PDE5 inhibitors is contraindicated. Caution is necessary with alpha-blockers and antihypertensives, which can lead to hypotensive events.
In addition, protease inhibitors, often used in HIV treatment, can elevate sildenafil levels in the bloodstream. Such elevation necessitates dose adjustments and close monitoring. Grapefruit juice may also increase serum sildenafil levels and should be avoided.
Silagra Side Effects
The adverse effects of Sildenafil 100 mg often relate to its vasodilatory properties. Common side effects include headache, facial flushing, and dizziness. More severe reactions such as priapism, vision changes, and auditory disturbances require immediate medical attention.
Patients should report prolonged erections lasting over four hours. This condition necessitates urgent care to prevent irreversible damage. Understanding potential side effects ensures timely management and prevents complications.
Purchase Silagra Without Prescription
Though online availability of Silagra without a prescription is prevalent, caution is advised. Illegitimate sources may sell counterfeit products. Such products pose safety risks due to unknown quality and strength.
- Consult healthcare professionals before purchase.
- Verify online pharmacies for authenticity.
- Ensure a prescription-based purchase for safe use.
Choosing a reputable source guarantees genuine Silagra, safeguarding patient health and ensuring therapeutic efficacy. Prioritizing patient safety above convenience prevents adverse outcomes.